{"id":15122,"date":"2017-10-10T18:30:57","date_gmt":"2017-10-10T18:30:57","guid":{"rendered":"https:\/\/staging.awgp.pt\/testes\/?p=15122"},"modified":"2025-04-22T15:20:38","modified_gmt":"2025-04-22T15:20:38","slug":"temporary-title-15122","status":"publish","type":"post","link":"https:\/\/staging.awgp.pt\/testes\/temporary-title-15122\/","title":{"rendered":"Iron Supplementation in Twin Pregnancy &#8211; The Benefit of Doubling the Iron Dose in Iron Deficient Pregnant Women: A Randomized Controlled Trial"},"content":{"rendered":"<style type=\"text\/css\"><\/style>[cmsmasters_row data_width=&#8221;boxed&#8221; data_padding_left=&#8221;3&#8243; data_padding_right=&#8221;3&#8243; data_top_style=&#8221;default&#8221; data_bot_style=&#8221;default&#8221; data_color=&#8221;default&#8221; data_bg_position=&#8221;top center&#8221; data_bg_repeat=&#8221;no-repeat&#8221; data_bg_attachment=&#8221;scroll&#8221; data_bg_size=&#8221;cover&#8221; data_bg_parallax_ratio=&#8221;0.5&#8243; data_padding_top=&#8221;0&#8243; data_padding_bottom=&#8221;50&#8243;][cmsmasters_column data_width=&#8221;1\/1&#8243;][cmsmasters_text animation_delay=&#8221;0&#8243;]<\/p>\n<p class=\"cit\"><span role=\"menubar\">Twin Res Hum Genet.<\/span>\u00a02017 Oct;20(5):419-424. doi: 10.1017\/thg.2017.43. Epub 2017 Aug 22.<\/p>\n<h2>Iron Supplementation in Twin Pregnancy &#8211; The Benefit of Doubling the Iron Dose in Iron Deficient Pregnant Women: A Randomized Controlled Trial<\/h2>\n<p class=\"auths\">Shinar S<sup>1<\/sup>,\u00a0Skornick-Rapaport A<sup>1<\/sup>,\u00a0Maslovitz S<sup>1<\/sup>.<\/p>\n<div class=\"afflist\">\n<p><strong><span class=\"ui-ncbitoggler-master-text\">Author information<\/span><\/strong><\/p>\n<div class=\"ui-helper-reset\" aria-live=\"assertive\">\n<dl class=\"ui-ncbi-toggler-slave-open ui-ncbitoggler ui-ncbitoggler-slave-open\" aria-hidden=\"false\">\n<dt><sup>1 &#8211; Lis Maternity Hospital,Department of Obstetrics and Gynecology,Sourasky Medical Center,Tel Aviv University,Tel Aviv,Israel.<\/sup><\/dt>\n<\/dl>\n<\/div>\n<\/div>\n<div class=\"abstr\">\n<p><strong>Abstract<\/strong><\/p>\n<div class=\"\">\n<p><strong>OBJECTIVE: <\/strong>To assess the efficacy of doubling the daily dose of iron supplement in iron-deficient women with twin pregnancies.<\/p>\n<p><strong>STUDY DESIGN: <\/strong>Using a prospective randomized controlled trial, iron-deficient women with twin gestations were randomized to receive a single or a double dose of daily iron from 16 weeks of gestation until 6 weeks postpartum. The primary outcome was hemoglobin at 32 weeks. Secondary outcomes included ferritin at 32 weeks, hemoglobin during pregnancy and postpartum, birth weights, preterm birth rate, gastrointestinal side effects, intravenous iron administration, and compliance with treatment.<\/p>\n<p><strong>RESULTS: <\/strong>Eighty-five and 87 women were randomized to receive one capsule (group A) or two capsules (group B) of 34 mg of ferrous sulfate, respectively. Mean hemoglobin (9.6 g\/dL and 9.7 g\/dL) and ferritin (8.6 ng\/ml and 8.5 ng\/ml) were similar in both groups A and B, respectively, at allocation. Hemoglobin in group B was significantly higher from 32 weeks onward, until 6 weeks postpartum. There were no significant differences in any of the secondary outcomes examined.<\/p>\n<p><strong>CONCLUSIONS: <\/strong>In twin pregnancies complicated by iron deficiency anemia, doubling the dose of iron increases hemoglobin and ferritin without worsening gastrointestinal side effects.<\/p>\n<\/div>\n<\/div>\n<div class=\"keywords\">\n<p><strong>KEYWORDS:\u00a0<\/strong>IDA; ferrous sulfate; iron deficiency anemia; iron supplement; nutrition; pregnancy; twin<\/p>\n<\/div>\n<p>[\/cmsmasters_text][cmsmasters_button button_type=&#8221;regular&#8221; button_link=&#8221;https:\/\/www.cambridge.org\/core\/journals\/twin-research-and-human-genetics\/article\/iron-supplementation-in-twin-pregnancy-the-benefit-of-doubling-the-iron-dose-in-iron-deficient-pregnant-women-a-randomized-controlled-trial\/3B43C78C153CCEB8BAC074E73D53C4BF#&#8221; button_target=&#8221;blank&#8221; button_text_align=&#8221;left&#8221; button_style=&#8221;cmsmasters_but_bg_slide_left&#8221; button_font_weight=&#8221;normal&#8221; button_font_style=&#8221;normal&#8221; button_border_style=&#8221;solid&#8221; animation_delay=&#8221;0&#8243;]Twin Research and Human Genetics[\/cmsmasters_button][\/cmsmasters_column][\/cmsmasters_row]\n","protected":false},"excerpt":{"rendered":"<p>[cmsmasters_row data_width=&#8221;boxed&#8221; data_padding_left=&#8221;3&#8243; data_padding_right=&#8221;3&#8243; data_top_style=&#8221;default&#8221; data_bot_style=&#8221;default&#8221; data_color=&#8221;default&#8221; data_bg_position=&#8221;top center&#8221; data_bg_repeat=&#8221;no-repeat&#8221; data_bg_attachment=&#8221;scroll&#8221; data_bg_size=&#8221;cover&#8221; data_bg_parallax_ratio=&#8221;0.5&#8243; data_padding_top=&#8221;0&#8243; data_padding_bottom=&#8221;50&#8243;][cmsmasters_column data_width=&#8221;1\/1&#8243;][cmsmasters_text animation_delay=&#8221;0&#8243;] Twin Res Hum Genet.\u00a02017 Oct;20(5):419-424. doi: 10.1017\/thg.2017.43. Epub 2017 Aug 22. Iron Supplementation in Twin Pregnancy &#8211; The Benefit of Doubling the Iron Dose in Iron Deficient Pregnant Women: A Randomized Controlled Trial Shinar S1,\u00a0Skornick-Rapaport A1,\u00a0Maslovitz S1. Author&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[102,97],"tags":[],"class_list":["post-15122","post","type-post","status-publish","format-standard","hentry","category-anemia-na-gravida","category-artigo-cientifico"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Iron Supplementation in Twin Pregnancy - The Benefit of Doubling the Iron Dose in Iron Deficient Pregnant Women: A Randomized Controlled Trial - AWGP - Testes<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"pt_PT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Iron Supplementation in Twin Pregnancy - The Benefit of Doubling the Iron Dose in Iron Deficient Pregnant Women: A Randomized Controlled Trial - AWGP - Testes\" \/>\n<meta property=\"og:description\" content=\"[cmsmasters_row data_width=&#8221;boxed&#8221; data_padding_left=&#8221;3&#8243; data_padding_right=&#8221;3&#8243; data_top_style=&#8221;default&#8221; data_bot_style=&#8221;default&#8221; data_color=&#8221;default&#8221; data_bg_position=&#8221;top center&#8221; data_bg_repeat=&#8221;no-repeat&#8221; data_bg_attachment=&#8221;scroll&#8221; data_bg_size=&#8221;cover&#8221; data_bg_parallax_ratio=&#8221;0.5&#8243; data_padding_top=&#8221;0&#8243; data_padding_bottom=&#8221;50&#8243;][cmsmasters_column data_width=&#8221;1\/1&#8243;][cmsmasters_text animation_delay=&#8221;0&#8243;] Twin Res Hum Genet.\u00a02017 Oct;20(5):419-424. doi: 10.1017\/thg.2017.43. Epub 2017 Aug 22. Iron Supplementation in Twin Pregnancy &#8211; The Benefit of Doubling the Iron Dose in Iron Deficient Pregnant Women: A Randomized Controlled Trial Shinar S1,\u00a0Skornick-Rapaport A1,\u00a0Maslovitz S1. 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